@Display Name The 152 should not interfere with other devices using the I2C bus on GPIO2/3 unless they happened to use the same I2C address as the 152. The I2C components on the 152 support up to 400 kHz, but we do not change the I2C speed from the default value in the library so it is likely running at 100 kHz.
It is possible that the extra bus capacitance of having the 152s along with your devices is slowing the edges enough to have issues. Are you using any additional pull-up resistors on SDA / SCL? You could try capturing the I2C comms on a scope in both scenarios to see the difference, and adding additional pull-ups may improve the communications.