AlexanderGDean

Hi @AlexanderGDean
The supplies should be protected, see the schematic:
https://digilent.com/reference/test-and-measurement/analog-discovery-2/hardware-design-guide
As usual, make sure the devices use the same ground level.
The AWG outputs are sensitive for back powering, specially when these are unpowered, before software connection.

Hi @AlexanderGDean,
I am not certain of the exact answer (maybe Attila will be able to offer some more details once it is regular working hours in his European timezone).
I know that based on Section 6.3 of the Hardware Design Guide, https://wiki.digilent.com/reference/test-and-measurement/analog-discovery-2/hardware-design-guide#power_supplies_and_control, that the particular IC in question for the User Supplies has low voltage drop reverse supply protection as well as analog undervoltage and overvoltage protection though I'm not readily able to determine the details of what those two line items mean from the related sections and equations of the guide, but perhaps you might find some insight from the listed information.
Thanks,
JColvin

Hi @AlexanderGDean
This crosstalk could between the wires which act as antennas.
This could be highly reduced by shielded cables but twisted wires also help a lot.
Twist the positive and negative scope inputs together and for single ended usage connect the negative to the ground near the test point; twist each of the used digital, trigger, wavegen and supply wire with ground.