Hello @BillySugger.
Please download and install the current version of InstaCal v6.74. Connect the USB-201 device and launch InstaCal. Close InstaCal after it has detected the device and then launch DAQami.
If the issue continues, the problem may be a corrupt setup file. Use Windows' File Explorer to browse to the 'C:\Users\{username}\Documents\Measurement Computing\' directory. There you should find a file called daqami.mcfg. Rename this file to daqami.bak and then restart DAQami. Let me know what happens.
Regards,
Fausto