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I tested the hat against another RPI (3B) and it's working fine. I think the original RPI (4B) that I used was defected. I had another hat stacked (RPI CAN Hat shield) along with the MCC-152 and that might have messed up the SPI pins... Thanks for the reply though. BTW there was no error message and no response if I tried to open the device from the GUI program. If I tried to run the python program I get a message "Error during opening port [...]".

SPI and I2C are both enabled. When I run the MCC DAT HAT Manager it is able to detect the MCC 152 from the List devices The address is correct but I am unable to open the device and write signal to the DIO and AO. Is there anything I am missing? I am running the latest Raspbian on Pi 4 with Python 3 installed. Is there anything I can check or probe on the HAT to verify it is working? Thank you. Leon